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Liver Tissue-specific Genes IGFALS,CYP3A4,SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer / 中国医学科学院学报

Yan-Yan ZHANG; Jing CAO; Xiao-Tong CHEN; Jun-Hui CHEN; Yu-Bao ZHENG.

Acta Academiae Medicinae Sinicae ; (6): 371-381, 2021.

Article in Chinese | WPRIM | ID: wpr-887869

ABSTRACT

Objective To explore the function and mechanism of related genes in the occurrence and development of liver cancer, and the possibility of key genes as potential biomarkers and prognostic indicators for the treatment of liver cancer.Methods We selected 4 datasets(GSE57957, GSE121248, GSE36376 and GSE14520)from the GEO database.With

Subject(s)

Humans , Biomarkers, Tumor/genetics , Carrier Proteins , Computational Biology , Cytochrome P-450 CYP2E1 , Cytochrome P-450 CYP3A , Gene Expression Profiling , Gene Expression Regulation, Neoplastic , Gene Regulatory Networks , Glycoproteins , Liver Neoplasms/genetics , Prognosis , Protein Interaction Maps

ABSTRACT

Subject(s)

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